Driving from San Diego to Las Vegas: The Fast WayDistance: 332 miles
Driving Time: 5 hours in good traffic
The primary highway between the San Diego and Las Vegas is I-15, passing through San Bernardino and Barstow. The directions are simple: just get onto I-15 and drive until you see all the neon lights.
The map above shows the fast route in general. Click on the map and you'll get a slightly larger version. If you'd like to see it even bigger, zoom in and out or get detailed driving directions for your road trip and explore what you might see along the way, go to the interactive version.
You might not believe that it snows in the desert, but as recently as 2010, I-15 was closed near the state line because of snow and ice in the mountain pass. Check road status on California highways between Los Angeles and the Nevada border at the Department of Transportation website or call 800-427-7623. Enter "15" get information about road repairs and closures. For conditions in Nevada, go here.
If your automobile contains restless people who need a break, you may want to stop at Calico Ghost Town just east of Barstow for a quick stretch of the legs.